Suppressor of Cytokine Signaling-1 (SOCS1) Inhibits Lymphocyte Recruitment into the Retina and Protects SOCS1 Transgenic Rats and Mice from Ocular Inflammation

摘要

This study reveals that Suppressor of cytokine signaling-1 mitigates uveitis by inhibiting the infiltration of inflammatory cells into the retina and conferring protection to retinal cells by inhibiting activities of proapoptotic cytokines.